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Identification of three novel RB1 mutations in Brazilian patients with retinoblastoma by “exon by exon” PCR mediated SSCP analysis

Aims: To carry out a retrospective study, screening for mutations of the entire coding region of RB1 and adjacent intronic regions in patients with retinoblastoma. Methods: Mutation screening in DNA extracts of formalin fixed, paraffin wax embedded tissues of 28 patients using combined “exon by exon...

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Detalhes bibliográficos
Main Authors: Braggio, E, Bonvicino, C R, Vargas, F R, Ferman, S, Eisenberg, A L A, Seuánez, H N
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 Journal of Clinical Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770321/
https://ncbi.nlm.nih.gov/pubmed/15166261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2003.014423
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