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Identification of APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis
The APC gene is a putative human tumor-suppressor gene responsible for adenomatous polyposis coli (APC), an inherited, autosomal dominant predisposition to colon cancer. It is also implicated in the development of sporadic colorectal tumors. The characterization of APC gene mutations in APC patients...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
1993
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1682198/ https://ncbi.nlm.nih.gov/pubmed/8381581 |
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