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Identification of three new mutations in the RB1 gene in patients with sporadic retinoblastoma in Colombia

Introduction. Retinoblastoma is a childhood cancer of the retina originated by altered or null retinoblastoma protein (pRb) expression. Genetic alterations in both RB1 alleles in the retinal cells are required for the development of retinoblastoma. In the sporadic form, non-hereditary RB1 gene mutat...

詳細記述

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書誌詳細
出版年:Biomédica
主要な著者: Martha Lucía Serrano, Juan José Yunis
フォーマット: Artigo
言語:Inglês
出版事項: Instituto Nacional de Salud 2013
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オンライン・アクセス:https://www.redalyc.org/articulo.oa?id=84326221007
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