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Identification of three new mutations in the RB1 gene in patients with sporadic retinoblastoma in Colombia

Introduction. Retinoblastoma is a childhood cancer of the retina originated by altered or null retinoblastoma protein (pRb) expression. Genetic alterations in both RB1 alleles in the retinal cells are required for the development of retinoblastoma. In the sporadic form, non-hereditary RB1 gene mutat...

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Bibliografski detalji
Izdano u:Biomédica
Glavni autori: Martha Lucía Serrano, Juan José Yunis
Format: Artigo
Jezik:Inglês
Izdano: Instituto Nacional de Salud 2013
Teme:
Online pristup:https://www.redalyc.org/articulo.oa?id=84326221007
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