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Synthesis of Miconazole and Analogs Through a Carbenoid Intermediate

An alternative synthesis for the preparation of miconazole,enilconazole and econazole is described. The process involves theintermolecular insertion of a carbenoid species to imidazole from α-diazoketones with copper acetylacetonate as the key reaction of thesynthesis route.

Furkejuvvon:
Bibliográfalaš dieđut
Publikašuvnnas:Journal of the Mexican Chemical Society
Váldodahkkit: Adriana Canul, Juan Manuel Serrano, Erick Cuevas, Raymundo Cruz, Joseph M. Muchowski
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Sociedad Química de México 2004
Fáttát:
Liŋkkat:https://www.redalyc.org/articulo.oa?id=47548110
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