Synthesis of Miconazole and Analogs Through a Carbenoid Intermediate
An alternative synthesis for the preparation of miconazole,enilconazole and econazole is described. The process involves theintermolecular insertion of a carbenoid species to imidazole from α-diazoketones with copper acetylacetonate as the key reaction of thesynthesis route.
Gardado en:
| Publicado en: | Journal of the Mexican Chemical Society |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Sociedad Química de México
2004
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| Assuntos: | |
| Acceso en liña: | https://www.redalyc.org/articulo.oa?id=47548110 |
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