Structure-activity of Sansalvamide A Derivatives and their Apoptotic Activity in the Pancreatic Cancer Cell Line PL-45

We report the structure-activity relationship (SAR) of forty Sansalvamide A (San A) derivatives against human pancreatic ductal adenicarcinoma cell line PL-45. Our comprehensive evaluation of these compounds utilizes: cytotoxicity based SAR, molecular modeling, and ApoAlert Annexin V apoptosis detec...

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Опубликовано в::	Journal of the Mexican Chemical Society
Главные авторы:	Rodrigo A. Rodríguez, Po-Shen Pan, Robert C. Vasko, Chung-Mao Pan, William S. Disman, Shelli R. McAlpine
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Sociedad Química de México 2008
Предметы:	Multidisciplinaria (Ciencias Naturales y Exactas)
Online-ссылка:	https://www.redalyc.org/articulo.oa?id=47512078005
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