Structure-activity of Sansalvamide A Derivatives and their Apoptotic Activity in the Pancreatic Cancer Cell Line PL-45

We report the structure-activity relationship (SAR) of forty Sansalvamide A (San A) derivatives against human pancreatic ductal adenicarcinoma cell line PL-45. Our comprehensive evaluation of these compounds utilizes: cytotoxicity based SAR, molecular modeling, and ApoAlert Annexin V apoptosis detec...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Journal of the Mexican Chemical Society
Hlavní autoři: Rodrigo A. Rodríguez, Po-Shen Pan, Robert C. Vasko, Chung-Mao Pan, William S. Disman, Shelli R. McAlpine
Médium: Artigo
Jazyk:Inglês
Vydáno: Sociedad Química de México 2008
Témata:
Química
Structure
apoptosis
Sansalvamide A
molecular modeling
activity relationship
On-line přístup:https://www.redalyc.org/articulo.oa?id=47512078005
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky