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The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease
Trypanosoma cruzi is highly sensitive to oxidative stress caused by reactive oxygen species. Trypanothione, theparasites major protection against oxidative stress, is kept reduced by trypanothione reductase, using NADPH; themajor source of the reduced coenzyme seems to be the pentose phosphate path...
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| Publicado no: | Anais da Academia Brasileira de Ciências |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academia Brasileira de Ciências
2007
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| Assuntos: | |
| Acesso em linha: | https://www.redalyc.org/articulo.oa?id=32779407 |
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