Multidrug resistance in tumour cells: characterisation of the multidrug resistant cell line K562-Lucena 1

Multidrug resistance to chemotherapy is a major obstacle in the treatment of cancer patients. The bestcharacterised mechanism responsible for multidrug resistance involves the expression of the MDR-1 geneproduct, P-glycoprotein. However, the resistance process is multifactorial. Studies of multidrug...

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Publicat a:Anais da Academia Brasileira de Ciências
Autors principals: Luis F. Marques-Santos, Vivian M. Rumjanek, Gilma S. Trindade, Karen Wagner-Souza, Michele C. Meletti-de-Oliveira, Raquel C. Maia, Márcia A. M. Capella
Format: Artigo
Idioma:Inglês
Publicat: Academia Brasileira de Ciências 2001
Matèries:
Multidisciplinaria (Ciencias Naturales y Exactas)
leukaemia
glycoprotein
chemosensitisers
multidrug resistance
Accés en línia:https://www.redalyc.org/articulo.oa?id=32773107
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