The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

Snail family genes encode DNA binding zinc finger proteins that act as transcriptional repressors. Mouse embryos deficient for the Snail (Sna) gene exhibit defects in the formation of the mesoderm germ layer. In Sna(−/−) mutant embryos, a mesoderm layer forms and mesodermal marker genes are induced...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Carver, Ethan A., Jiang, Rulang, Lan, Yu, Oram, Kathleen F., Gridley, Thomas
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2001
Subjects:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.23.8184-8188.2001
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