The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

Snail family genes encode DNA binding zinc finger proteins that act as transcriptional repressors. Mouse embryos deficient for the Snail (Sna) gene exhibit defects in the formation of the mesoderm germ layer. In Sna(−/−) mutant embryos, a mesoderm layer forms and mesodermal marker genes are induced...

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Bibliografski detalji
Glavni autori: Carver, Ethan A., Jiang, Rulang, Lan, Yu, Oram, Kathleen F., Gridley, Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC99982/
https://ncbi.nlm.nih.gov/pubmed/11689706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.8184-8188.2001
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