The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

Snail family genes encode DNA binding zinc finger proteins that act as transcriptional repressors. Mouse embryos deficient for the Snail (Sna) gene exhibit defects in the formation of the mesoderm germ layer. In Sna(−/−) mutant embryos, a mesoderm layer forms and mesodermal marker genes are induced...

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Detalhes bibliográficos
Main Authors: Carver, Ethan A., Jiang, Rulang, Lan, Yu, Oram, Kathleen F., Gridley, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99982/
https://ncbi.nlm.nih.gov/pubmed/11689706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.8184-8188.2001
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