Isolation and Characterization of Point Mutations in Mismatch Repair Genes That Destabilize Microsatellites in Yeast

The stability of simple repetitive DNA sequences (microsatellites) is a sensitive indicator of the ability of a cell to repair DNA mismatches. In a genetic screen for yeast mutants with elevated microsatellite instability, we identified strains containing point mutations in the yeast mismatch repair...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Sia, Elaine Ayres, Dominska, Margaret, Stefanovic, Lela, Petes, Thomas D.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2001
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99980/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.23.8157-8167.2001
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