Specific Double-Stranded RNA Interference in Undifferentiated Mouse Embryonic Stem Cells

Specific mRNA degradation mediated by double-stranded RNA (dsRNA) interference (RNAi) is a powerful way of suppressing gene expression in plants, nematodes, and fungal, insect, and protozoan systems. However, only a few cases of RNAi have been reported in mammalian systems. Here, we investigated the...

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Detalhes bibliográficos
Main Authors: Yang, Shicheng, Tutton, Stephen, Pierce, Eric, Yoon, Kyonggeun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99950/
https://ncbi.nlm.nih.gov/pubmed/11604515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7807-7816.2001
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