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Mouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA Breaks

Embryonic stem (ES) cells give rise to all cell types of an organism. Since mutations at this embryonic stage would affect all cells and be detrimental to the overall health of an organism, robust mechanisms must exist to ensure that genomic integrity is maintained. To test this proposition, we comp...

詳細記述

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書誌詳細
主要な著者: Tichy, Elisia D., Pillai, Resmi, Deng, Li, Liang, Li, Tischfield, Jay, Schwemberger, Sandy J., Babcock, George F., Stambrook, Peter J.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128311/
https://ncbi.nlm.nih.gov/pubmed/20446816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2010.0058
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