Mouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA Breaks

Embryonic stem (ES) cells give rise to all cell types of an organism. Since mutations at this embryonic stage would affect all cells and be detrimental to the overall health of an organism, robust mechanisms must exist to ensure that genomic integrity is maintained. To test this proposition, we comp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tichy, Elisia D., Pillai, Resmi, Deng, Li, Liang, Li, Tischfield, Jay, Schwemberger, Sandy J., Babcock, George F., Stambrook, Peter J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Mary Ann Liebert, Inc. 2010
विषय:
Original Research Reports
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128311/
https://ncbi.nlm.nih.gov/pubmed/20446816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2010.0058
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