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Mismatch and Base Excision Repair Proficiency in Murine Embryonic Stem Cells

Accumulation of mutations in embryonic stem (ES) cells would be detrimental to an embryo derived from these cells, and would adversely affect multiple organ systems and tissue types. ES cells have evolved multiple mechanisms to preserve genomic integrity that extend beyond those found in differentia...

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Autors principals: Tichy, Elisia D., Liang, Li, Deng, Li, Tischfield, Jay, Schwemberger, Sandy, Babcock, George, Stambrook, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062712/
https://ncbi.nlm.nih.gov/pubmed/21315663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.01.008
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