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Mismatch and Base Excision Repair Proficiency in Murine Embryonic Stem Cells

Accumulation of mutations in embryonic stem (ES) cells would be detrimental to an embryo derived from these cells, and would adversely affect multiple organ systems and tissue types. ES cells have evolved multiple mechanisms to preserve genomic integrity that extend beyond those found in differentia...

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Detalhes bibliográficos
Main Authors: Tichy, Elisia D., Liang, Li, Deng, Li, Tischfield, Jay, Schwemberger, Sandy, Babcock, George, Stambrook, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062712/
https://ncbi.nlm.nih.gov/pubmed/21315663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.01.008
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