Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo

GCN5 is a histone acetyltransferase (HAT) originally identified in Saccharomyces cerevisiae and required for transcription of specific genes within chromatin as part of the SAGA (SPT-ADA-GCN5 acetylase) coactivator complex. Mammalian cells have two distinct GCN5 homologs (PCAF and GCN5L) that have b...

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Detalhes bibliográficos
Main Authors: Martinez, Ernest, Palhan, Vikas B., Tjernberg, Agneta, Lymar, Elena S., Gamper, Armin M., Kundu, Tapas K., Chait, Brian T., Roeder, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99856/
https://ncbi.nlm.nih.gov/pubmed/11564863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.6782-6795.2001
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