General Transcriptional Coactivator PC4 Activates p53 Function

The function of p53 is modulated by several transcriptional coactivators that regulate its tumor suppressor activity. Here we report that human transcriptional coactivator PC4 enhances the DNA binding of p53 to its cognate site in vitro and directly interacts with p53 in vivo. In vitro interaction s...

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Detalhes bibliográficos
Main Authors: Banerjee, Sourav, Kumar, B. R. Prashanth, Kundu, Tapas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC350566/
https://ncbi.nlm.nih.gov/pubmed/14966284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.2052-2062.2004
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