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General Transcriptional Coactivator PC4 Activates p53 Function
The function of p53 is modulated by several transcriptional coactivators that regulate its tumor suppressor activity. Here we report that human transcriptional coactivator PC4 enhances the DNA binding of p53 to its cognate site in vitro and directly interacts with p53 in vivo. In vitro interaction s...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC350566/ https://ncbi.nlm.nih.gov/pubmed/14966284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.2052-2062.2004 |
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