General Transcriptional Coactivator PC4 Activates p53 Function

The function of p53 is modulated by several transcriptional coactivators that regulate its tumor suppressor activity. Here we report that human transcriptional coactivator PC4 enhances the DNA binding of p53 to its cognate site in vitro and directly interacts with p53 in vivo. In vitro interaction s...

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Bibliografiska uppgifter
Huvudupphovsmän: Banerjee, Sourav, Kumar, B. R. Prashanth, Kundu, Tapas K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Transcriptional Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC350566/
https://ncbi.nlm.nih.gov/pubmed/14966284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.2052-2062.2004
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