Allosteric inhibitors of telomerase: oligonucleotide N3′→P5′ phosphoramidates

Telomerase is a ribonucleoprotein responsible for maintaining telomeres in nearly all eukaryotic cells. The enzyme is able to utilize a short segment of its RNA subunit as the template for the reverse transcription of d(TTAGGG) repeats onto the ends of human chromosomes. Transfection with telomerase...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Pruzan, Ronald, Pongracz, Krisztina, Gietzen, Kimberly, Wallweber, Gerald, Gryaznov, Sergei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11788719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.2.559
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