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Mutational fingerprints of aging

Using a lacZ plasmid transgenic mouse model, spectra of spontaneous point mutations were determined in brain, heart, liver, spleen and small intestine in young and old mice. While similar at a young age, the mutation spectra among these organs were significantly different in old age. In brain and he...

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Podrobná bibliografie
Hlavní autoři: Dollé, Martijn E. T., Snyder, Wendy K., Dunson, David B., Vijg, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC99828/
https://ncbi.nlm.nih.gov/pubmed/11788717
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