Histone Deacetylase Activity Represses Gamma Interferon-Inducible HLA-DR Gene Expression following the Establishment of a DNase I-Hypersensitive Chromatin Conformation

Expression of the retinoblastoma tumor suppressor protein (Rb) is required for gamma interferon (IFN-γ)-inducible major histocompatibility complex class II gene expression and transcriptionally productive HLA-DRA promoter occupancy in several human tumor cell lines. Treatment of these Rb-defective t...

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Bibliographic Details
Main Authors: Osborne, Aaron, Zhang, Hongquan, Yang, Wen-Ming, Seto, Edward, Blanck, George
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC99796/
https://ncbi.nlm.nih.gov/pubmed/11533238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6495-6506.2001
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