Development of an In Vitro Bioassay for Clostridium botulinum Type B Neurotoxin in Foods That Is More Sensitive than the Mouse Bioassay

A novel, in vitro bioassay for detection of the botulinum type B neurotoxin in a range of media was developed. The assay is amplified by the enzymic activity of the neurotoxin’s light chain and includes the following three stages: first, a small, monoclonal antibody-based immunoaffinity column captu...

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Bibliografiske detaljer
Main Authors: Wictome, Matthew, Newton, Kirsti, Jameson, Karen, Hallis, Bassam, Dunnigan, Paul, Mackay, Eric, Clarke, Sally, Taylor, Richard, Gaze, Joy, Foster, Keith, Shone, Clifford
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Food Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC99701/
https://ncbi.nlm.nih.gov/pubmed/10473376
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