Combined, Functional Genomic-Biochemical Approach to Intermediary Metabolism: Interaction of Acivicin, a Glutamine Amidotransferase Inhibitor, with Escherichia coli K-12

Acivicin, a modified amino acid natural product, is a glutamine analog. Thus, it might interfere with metabolism by hindering glutamine transport, formation, or usage in processes such as transamidation and translation. This molecule prevented the growth of Escherichia coli in minimal medium unless...

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Bibliografische gegevens
Hoofdauteurs: Smulski, Dana R., Huang, Lixuan L., McCluskey, Michael P., Reeve, Mary Jane Gladnick, Vollmer, Amy C., Van Dyk, Tina K., LaRossa, Robert A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2001
Onderwerpen:
Genetics and Molecular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC99633/
https://ncbi.nlm.nih.gov/pubmed/11344143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.11.3353-3364.2001
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