Combined, Functional Genomic-Biochemical Approach to Intermediary Metabolism: Interaction of Acivicin, a Glutamine Amidotransferase Inhibitor, with Escherichia coli K-12

Acivicin, a modified amino acid natural product, is a glutamine analog. Thus, it might interfere with metabolism by hindering glutamine transport, formation, or usage in processes such as transamidation and translation. This molecule prevented the growth of Escherichia coli in minimal medium unless...

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Опубликовано в::	J Bacteriol
Главные авторы:	Smulski, Dana R., Huang, Lixuan L., McCluskey, Michael P., Reeve, Mary Jane Gladnick, Vollmer, Amy C., Van Dyk, Tina K., LaRossa, Robert A.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2001
Предметы:	Genetics and Molecular Biology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11344143/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.11.3353-3364.2001
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