The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains of Mycobacterium tuberculosis in Mice

Murine macrophages effect potent antimycobacterial function via the production of nitric oxide by the inducible isoform of the enzyme nitric oxide synthase (NOS2). The protective role of reactive nitrogen intermediates (RNI) against Mycobacterium tuberculosis infection has been well established in v...

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Bibliografiset tiedot
Päätekijät: Scanga, Charles A., Mohan, Vellore P., Tanaka, Kathryn, Alland, David, Flynn, JoAnne L., Chan, John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Bacterial Infections
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC98866/
https://ncbi.nlm.nih.gov/pubmed/11705952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7711-7717.2001
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