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Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages.

Lipophosphoglycan (LPG) glycoconjugates from promastigotes of Leishmania were not able to induce the expression of the cytokine-inducible nitric oxide synthase (iNOS) by the murine macrophage cell line, J774. However, they synergize with interferon gamma to stimulate the macrophages to express high...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Proudfoot, L, Nikolaev, A V, Feng, G J, Wei, W Q, Ferguson, M A, Brimacombe, J S, Liew, F Y
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10984
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