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Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages.

Lipophosphoglycan (LPG) glycoconjugates from promastigotes of Leishmania were not able to induce the expression of the cytokine-inducible nitric oxide synthase (iNOS) by the murine macrophage cell line, J774. However, they synergize with interferon gamma to stimulate the macrophages to express high...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Proudfoot, L, Nikolaev, A V, Feng, G J, Wei, W Q, Ferguson, M A, Brimacombe, J S, Liew, F Y
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10984
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