The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains of Mycobacterium tuberculosis in Mice

Murine macrophages effect potent antimycobacterial function via the production of nitric oxide by the inducible isoform of the enzyme nitric oxide synthase (NOS2). The protective role of reactive nitrogen intermediates (RNI) against Mycobacterium tuberculosis infection has been well established in v...

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Detalhes bibliográficos
Main Authors: Scanga, Charles A., Mohan, Vellore P., Tanaka, Kathryn, Alland, David, Flynn, JoAnne L., Chan, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98866/
https://ncbi.nlm.nih.gov/pubmed/11705952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7711-7717.2001
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