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Role of Gamma Interferon in the Pathogenesis of Severe Schistosomiasis in Interleukin-4-Deficient Mice

In the absence of interleukin-4 (IL-4), infection with Schistosoma mansoni leads to a severe fatal disease rather than the chronic survivable condition that occurs in wild-type (WT) mice. Because the sustained production of NO most closely correlates to weight loss and fatality in infected IL-4(−/−)...

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Autores principales: La Flamme, Anne Camille, Patton, Elisabeth A., Pearce, Edward J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC98833/
https://ncbi.nlm.nih.gov/pubmed/11705919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7445-7452.2001
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