Role of Gamma Interferon in the Pathogenesis of Severe Schistosomiasis in Interleukin-4-Deficient Mice

In the absence of interleukin-4 (IL-4), infection with Schistosoma mansoni leads to a severe fatal disease rather than the chronic survivable condition that occurs in wild-type (WT) mice. Because the sustained production of NO most closely correlates to weight loss and fatality in infected IL-4(−/−)...

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Pubblicato in:	Infect Immun
Autori principali:	La Flamme, Anne Camille, Patton, Elisabeth A., Pearce, Edward J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11705919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.12.7445-7452.2001
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