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Interleukin-4 and Transforming Growth Factor β Have Opposing Regulatory Effects on Gamma Interferon-Mediated Inhibition of Cryptosporidium parvum Reproduction

It was shown previously that enterocytes activated by gamma interferon (IFN-γ) are efficient effector cells in the killing of Cryptosporidium parvum. How this function is regulated is not clearly understood, but transforming growth factor β (TGF-β) and the Th2 regulatory cytokines may play a role. U...

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Autori principali: Lean, I.-Sarah, McDonald, Stuart A. C., Bajaj-Elliott, Mona, Pollok, Richard C. G., Farthing, Michael J. G., McDonald, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC165998/
https://ncbi.nlm.nih.gov/pubmed/12874337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4580-4585.2003
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