Mycobacterium tuberculosisChaperonin 60.1 Is a More Potent Cytokine Stimulator than Chaperonin 60.2 (Hsp 65) and Contains a CD14-Binding Domain

Much attention has focused on the Mycobacterium tuberculosis molecular chaperone chaperonin (Cpn) 60.2 (Hsp 65) in the pathology of tuberculosis because of its immunogenicity and ability to directly activate human monocytes and vascular endothelial cells. However, M. tuberculosis is one of a small g...

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Main Authors: Lewthwaite, Jo C., Coates, Anthony R. M., Tormay, Peter, Singh, Mahavir, Mascagni, Paolo, Poole, Stephen, Roberts, Michael, Sharp, Lindsay, Henderson, Brian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2001
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98821/
https://ncbi.nlm.nih.gov/pubmed/11705907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7349-7355.2001
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