Mycobacterium tuberculosisChaperonin 60.1 Is a More Potent Cytokine Stimulator than Chaperonin 60.2 (Hsp 65) and Contains a CD14-Binding Domain

Much attention has focused on the Mycobacterium tuberculosis molecular chaperone chaperonin (Cpn) 60.2 (Hsp 65) in the pathology of tuberculosis because of its immunogenicity and ability to directly activate human monocytes and vascular endothelial cells. However, M. tuberculosis is one of a small g...

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Autors principals: Lewthwaite, Jo C., Coates, Anthony R. M., Tormay, Peter, Singh, Mahavir, Mascagni, Paolo, Poole, Stephen, Roberts, Michael, Sharp, Lindsay, Henderson, Brian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98821/
https://ncbi.nlm.nih.gov/pubmed/11705907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7349-7355.2001
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