Characterization of the Enzymatic Component of the ADP-Ribosyltransferase Toxin CDTa from Clostridium difficile

Certain strains of Clostridium difficile produce the ADP-ribosyltransferase CDT, which is a binary actin ADP-ribosylating toxin. The toxin consists of the binding component CDTb, which mediates receptor binding and cellular uptake, and the enzyme component CDTa. Here we studied the enzyme component...

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Autores principales: Gülke, Irene, Pfeifer, Gunther, Liese, Jan, Fritz, Michaela, Hofmann, Fred, Aktories, Klaus, Barth, Holger
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC98728/
https://ncbi.nlm.nih.gov/pubmed/11553537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6004-6011.2001
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