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Characterization of the Enzymatic Component of the ADP-Ribosyltransferase Toxin CDTa from Clostridium difficile

Certain strains of Clostridium difficile produce the ADP-ribosyltransferase CDT, which is a binary actin ADP-ribosylating toxin. The toxin consists of the binding component CDTb, which mediates receptor binding and cellular uptake, and the enzyme component CDTa. Here we studied the enzyme component...

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Udgivet i:Infect Immun
Principais autores: Gülke, Irene, Pfeifer, Gunther, Liese, Jan, Fritz, Michaela, Hofmann, Fred, Aktories, Klaus, Barth, Holger
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98728/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.10.6004-6011.2001
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