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Cytolethal Distending Toxin Demonstrates Genotoxic Activity in a Yeast Model

Cytolethal distending toxins (CDTs) are multisubunit proteins produced by a variety of bacterial pathogens that cause enlargement, cell cycle arrest, and apoptosis in mammalian cells. While their function remains uncertain, recent studies suggest that they can act as intracellular DNases in mammalia...

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Autors principals: Hassane, Duane C., Lee, Robert B., Mendenhall, Michael D., Pickett, Carol L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98692/
https://ncbi.nlm.nih.gov/pubmed/11500452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5752-5759.2001
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