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Multistage Multiantigen Heterologous Prime Boost Vaccine for Plasmodium knowlesi Malaria Provides Partial Protection in Rhesus Macaques

A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a multicomponent, multistage DNA vaccine for the simian malaria species Plasmodium knowlesi including...

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Autors principals: Rogers, William O., Baird, J. Kevin, Kumar, Anita, Tine, John A., Weiss, Walter, Aguiar, João C., Gowda, Kalpana, Gwadz, Robert, Kumar, Sanjai, Gold, Mark, Hoffman, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98670/
https://ncbi.nlm.nih.gov/pubmed/11500430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5565-5572.2001
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