Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques

Tuberculosis (TB) still is the principal cause of death from infectious disease and improved vaccination strategies are required to reduce the disease burden and break TB transmission. Here, we investigated different routes of administration of vectored subunit vaccines based on chimpanzee-derived a...

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Published in:NPJ Vaccines
Main Authors: Vierboom, Michel P. M., Chenine, Agnes L., Darrah, Patricia A., Vervenne, Richard A. W., Boot, Charelle, Hofman, Sam O., Sombroek, Claudia C., Dijkman, Karin, Khayum, Mohamed A., Stammes, Marieke A., Haanstra, Krista G., Hoffmann, Chantal, Schmitt, Doris, Silvestre, Nathalie, White, Alexander G., Borish, H. Jacob, Seder, Robert A., Ouaked, Nadia, Leung-Theung-Long, Stephane, Inchauspé, Geneviève, Anantha, Ravi, Limbach, Mary, Evans, Thomas G., Casimiro, Danilo, Lempicki, Maria, Laddy, Dominick J., Bonavia, Aurelio, Verreck, Frank A. W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224290/
https://ncbi.nlm.nih.gov/pubmed/32435513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0189-2
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