Meningococcal Outer Membrane Vesicle Vaccine Given Intranasally Can Induce Immunological Memory and Booster Responses without Evidence of Tolerance

We have studied the ability of outer membrane vesicle (OMV) vaccines from Neisseria meningitidis serogroup B to induce vaccine-specific antibody and spleen cell proliferative responses in mice after being administered intranasally (i.n.) and/or subcutaneously (s.c.). A series of four weekly i.n. dos...

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Autores principales: Bakke, Hilde, Lie, Kristian, Haugen, Inger Lise, Korsvold, Gro Ellen, Høiby, E. Arne, Næss, Lisbeth Meyer, Holst, Johan, Aaberge, Ingeborg S., Oftung, Fredrik, Haneberg, Bjørn
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC98594/
https://ncbi.nlm.nih.gov/pubmed/11447180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.5010-5015.2001
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