Meningococcal Outer Membrane Vesicle Vaccine Given Intranasally Can Induce Immunological Memory and Booster Responses without Evidence of Tolerance

We have studied the ability of outer membrane vesicle (OMV) vaccines from Neisseria meningitidis serogroup B to induce vaccine-specific antibody and spleen cell proliferative responses in mice after being administered intranasally (i.n.) and/or subcutaneously (s.c.). A series of four weekly i.n. dos...

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Bibliographic Details
Main Authors: Bakke, Hilde, Lie, Kristian, Haugen, Inger Lise, Korsvold, Gro Ellen, Høiby, E. Arne, Næss, Lisbeth Meyer, Holst, Johan, Aaberge, Ingeborg S., Oftung, Fredrik, Haneberg, Bjørn
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC98594/
https://ncbi.nlm.nih.gov/pubmed/11447180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.5010-5015.2001
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