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Facilitated Intranasal Induction of Mucosal and Systemic Immunity to Mutans Streptococcal Glucosyltransferase Peptide Vaccines

Synthetic peptide vaccines which are derived from functional domains of Streptococcus mutans glucosyltransferases (GTF) have been shown to induce protective immunity in Sprague-Dawley rats after subcutaneous injection in the salivary gland region. Since mucosal induction of salivary immunity would b...

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Detalles Bibliográficos
Main Authors: Smith, Daniel J., King, William F., Barnes, Leigh A., Trantolo, Debra, Wise, Donald L., Taubman, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98563/
https://ncbi.nlm.nih.gov/pubmed/11447149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.4767-4773.2001
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