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Facilitated Intranasal Induction of Mucosal and Systemic Immunity to Mutans Streptococcal Glucosyltransferase Peptide Vaccines

Synthetic peptide vaccines which are derived from functional domains of Streptococcus mutans glucosyltransferases (GTF) have been shown to induce protective immunity in Sprague-Dawley rats after subcutaneous injection in the salivary gland region. Since mucosal induction of salivary immunity would b...

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Autors principals: Smith, Daniel J., King, William F., Barnes, Leigh A., Trantolo, Debra, Wise, Donald L., Taubman, Martin A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98563/
https://ncbi.nlm.nih.gov/pubmed/11447149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.4767-4773.2001
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