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Coimmunization with Complementary Glucosyltransferase Peptides Results in Enhanced Immunogenicity and Protection against Dental Caries

Peptide constructs from the catalytic (CAT) and glucan-binding (GLU) regions of the mutans streptococcal glucosyltransferase enzymes (GTF) can provide immunity to dental caries infection. A strategy of coimmunization was tested to determine whether protection could be enhanced. Rats were immunized w...

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Main Authors: Taubman, Martin A., Smith, Daniel J., Holmberg, Cynthia J., Eastcott, Jean W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97477/
https://ncbi.nlm.nih.gov/pubmed/10768962
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