Coimmunization with Complementary Glucosyltransferase Peptides Results in Enhanced Immunogenicity and Protection against Dental Caries

Peptide constructs from the catalytic (CAT) and glucan-binding (GLU) regions of the mutans streptococcal glucosyltransferase enzymes (GTF) can provide immunity to dental caries infection. A strategy of coimmunization was tested to determine whether protection could be enhanced. Rats were immunized w...

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Pubblicato in:	Infect Immun
Autori principali:	Taubman, Martin A., Smith, Daniel J., Holmberg, Cynthia J., Eastcott, Jean W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768962/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2698-2703.2000
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