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Facilitated Intranasal Induction of Mucosal and Systemic Immunity to Mutans Streptococcal Glucosyltransferase Peptide Vaccines

Synthetic peptide vaccines which are derived from functional domains of Streptococcus mutans glucosyltransferases (GTF) have been shown to induce protective immunity in Sprague-Dawley rats after subcutaneous injection in the salivary gland region. Since mucosal induction of salivary immunity would b...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Smith, Daniel J., King, William F., Barnes, Leigh A., Trantolo, Debra, Wise, Donald L., Taubman, Martin A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447149/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.8.4767-4773.2001
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