Synthetic Polysaccharide Type 3-Related Di-, Tri-, and Tetrasaccharide–CRM(197) Conjugates Induce Protection against Streptococcus pneumoniae Type 3 in Mice

Di-, tri-, and tetrasaccharides, synthesized according to the chemical structure of pneumococcal polysaccharide type 3 (PS3), were coupled to the cross-reactive material (CRM(197)) of modified diphtheria toxin in different molar carbohydrate/protein ratios using the squarate coupling method. To stud...

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Εκδόθηκε σε:	Infect Immun
Κύριοι συγγραφείς:	Benaissa-Trouw, Barry, Lefeber, Dirk J., Kamerling, Johannis P., Vliegenthart, Johannes F. G., Kraaijeveld, Kees, Snippe, Harm
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2001
Θέματα:	Microbial Immunity and Vaccines
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11402020/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4698-4701.2001
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