Antigenic Diversity among Helicobacter pylori Vacuolating Toxins

Helicobacter pylori vacuolating cytotoxin (VacA) is a secreted protein that induces vacuolation of epithelial cells. To study VacA structure and function, we immunized mice with purified type s1-m1 VacA from H. pylori strain 60190 and generated a panel of 10 immunoglobulin G1κ anti-VacA monoclonal a...

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Autori principali: Vinion-Dubiel, Arlene D., McClain, Mark S., Cao, Ping, Mernaugh, Raymond L., Cover, Timothy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98503/
https://ncbi.nlm.nih.gov/pubmed/11401970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4329-4336.2001
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