Antigenic Diversity among Helicobacter pylori Vacuolating Toxins

Helicobacter pylori vacuolating cytotoxin (VacA) is a secreted protein that induces vacuolation of epithelial cells. To study VacA structure and function, we immunized mice with purified type s1-m1 VacA from H. pylori strain 60190 and generated a panel of 10 immunoglobulin G1κ anti-VacA monoclonal a...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Vinion-Dubiel, Arlene D., McClain, Mark S., Cao, Ping, Mernaugh, Raymond L., Cover, Timothy L.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2001
Subjects:	Molecular Pathogenesis
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11401970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4329-4336.2001
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