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Down-Regulated Lymphoproliferation Coincides with Parasite Maturation and with the Collapse of Both Gamma Interferon and Interleukin-4 Responses in a Bovine Model of Onchocerciasis

Onchocerciasis is a debilitating parasitic infection caused by the filarial nematode Onchocerca volvulus. Infections are chronic, and persistence of the parasites for several years argues for highly adapted mechanisms of immune evasion. Due to the restricted host repertoire of O. volvulus, we have u...

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Autors principals: Graham, Simon P., Trees, Alexander J., Collins, Robert A., Moore, Davina M., Guy, Francis M., Taylor, Mark J., Bianco, Albert E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98501/
https://ncbi.nlm.nih.gov/pubmed/11401968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4313-4319.2001
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