Transfected Plasmodium knowlesi Produces Bioactive Host Gamma Interferon: a New Perspective for Modulating Immune Responses to Malaria Parasites

Transgenic pathogenic microorganisms expressing host cytokines such as gamma interferon (IFN-γ) have been shown to manipulate host-pathogen interaction, leading to immunomodulation and enhanced protection. Expression of host cytokines in malaria parasites offers the opportunity to investigate the po...

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Bibliographic Details
Main Authors: Ozwara, Hastings, Langermans, Jan A. M., Kocken, Clemens H. M., van der Wel, Annemarie, van der Meide, Peter H., Vervenne, Richard A. W., Mwenda, Jason M., Thomas, Alan W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC166026/
https://ncbi.nlm.nih.gov/pubmed/12874315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4375-4381.2003
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