Transfected Plasmodium knowlesi Produces Bioactive Host Gamma Interferon: a New Perspective for Modulating Immune Responses to Malaria Parasites

Transgenic pathogenic microorganisms expressing host cytokines such as gamma interferon (IFN-γ) have been shown to manipulate host-pathogen interaction, leading to immunomodulation and enhanced protection. Expression of host cytokines in malaria parasites offers the opportunity to investigate the po...

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Main Authors: Ozwara, Hastings, Langermans, Jan A. M., Kocken, Clemens H. M., van der Wel, Annemarie, van der Meide, Peter H., Vervenne, Richard A. W., Mwenda, Jason M., Thomas, Alan W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC166026/
https://ncbi.nlm.nih.gov/pubmed/12874315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4375-4381.2003
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